FBLN3 antibody

Catalog No. ABIN2721180

This Mouse Monoclonal antibody specifically detects FBLN3 in WB and FACS. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for FBLN3 antibody (ABIN2721180)

Target: FBLN3 (Fibulin 3 (FBLN3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FBLN3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 1D9

Product Details anti-FBLN3 Antibody

Characteristics: Homo sapiens EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human EFEMP1(NP_004096) produced in HEK293T cell.

Isotype: IgG2a

Application Details

Application Notes: WB 1:200~500, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-FBLN3 antibody (ABIN2721180)

Han, Veeneman, El-Sawy, Day, Day, Tomlins, Keller: "Fibulin-3 promotes muscle-invasive bladder cancer." in: Oncogene, Vol. 36, Issue 37, pp. 5243-5251, (2017) (PubMed).

Target Details for FBLN3

Target: FBLN3 (Fibulin 3 (FBLN3))

Alternative Name: EFEMP1

Background: This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.[provided by RefSeq].

Molecular Weight: 52.7 kDa

Gene ID: 2202

NCBI Accession: NM_004105

HGNC: 2202

Pathways: EGFR Signaling Pathway